MallowbyNames

Despina

des-PEE-nah · The name means 'mistress' or 'lady,' ultimately from Greek 'despoina' (mistress of the house).

2025 rank (girls)
#14,942
Babies named in 2025
5
Peak popularity
1976
2025 frequency
1 in 321,453 girls
Usually for
Girls
Trend
Holding steady

Holding steady, #14,942 for girls today.

Popularity of Despina since 1914

Babies named Despina per year in U.S. Social Security records.

122436192019602000Most births 1976Girls
Data table (by decade)
DecadeGirls
1910s44
1920s136
1930s108
1940s69
1950s84
1960s178
1970s242
1980s196
1990s151
2000s136
2010s114
2020s65

Meaning & origin

Despina is a Greek name with deep mythological roots, referring to the 'mistress' or 'lady' of the household. In the United States, it has remained rare, with its peak frequency in 1976, when it was most popular among families with Greek heritage. Data from the Social Security Administration shows that since 1914, when it was first recorded in the U.S., the name has never broken into the top 1000. Its trajectory is stable, appealing to those seeking a distinctive name with classical origins. The name is strongly associated with Greek culture and is sometimes given to honor family traditions.

Despina is a Greek female name derived from 'despoina' (δέσποινα), meaning 'mistress' or 'lady of the house.' In Greek mythology, Despoina was a daughter of Poseidon and Demeter, associated with the Arcadian mysteries. The name has been borne by figures in Greek history and is common in modern Greece and among the Greek diaspora.

Nicknames & variants

Nicknames: Des, Despy, Pina

Variants: Despinia, Despoina

Sibling names for Despina

Names that share Despina's style, for a brother or sister.

A parent animal hugging its little one, the personalized name page

D is for Despina, our favorite little girl.

D is for Despina…”

In a Mallowby alphabet book, Despina's letter becomes Despina's page: hand-illustrated, printed hardcover or paperback, made just for them.

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Questions parents ask

What does the name Despina mean?
Despina means 'mistress' or 'lady,' from the Greek word 'despoina.'
How popular is the name Despina?
Despina is rare in the United States. As of 2025, it ranked 14,942 and is given to about 1 in 321,453 babies, with its highest popularity in 1976.
Is Despina a girl's name?
Yes, Despina is exclusively a girl's name.